Since you have a time frame for when it stopped working, you can start by looking at which mods you added or which mods you have updated in that time. You can sort subscriptions by Date Updated to easily see. It would be a mod that was added or updated in the time since the shortcut was working correctly.
Then to test unsubscribe the mod(s) that fit the time frame, start the game and load a new city, then test if the shortcut works again. If it does, add the mods back one (or a few) at a time until you find the one interfering.
If it's a lot of mods, I'd be happy to take a look at the list and give some ideas as to which ones are more likely to play a role.