Sorry about the issue! Looking at your log file, the game seems to be running out of memory during the startup process. I would recommend restarting your computer and closing any unnecessary applications. Then, when you open the game, avoid interacting with it until it’s fully loaded.
If the issue persists, please upload your crash report(s) from C:/Users/Wenhao/AppData/Local/Temp/Eleventh Hour Games/Last Epoch/Crashes, as indicated by your log file.
We are working on optimization with each patch, but unfortunately these issues do happen sometimes.