" wrote: I've encountered an issue that appears when I reserve life with an aura using Arrogance Support while having the Agnostic Keystone allocated. Agnostic will drain my mana despite having the maximum amount of life.
This would be affecting all Agnostic builds reserving life.
Thanks for your report, this is intended as you're not on Full Life because you have Life reserved.
Mark_GGG has also talked a little about it here: