But they probably aren't the reason for the game crashing. The most common reason is running out of memory. If you haven't specified a size for your pagefile, that would be the place to start, as the game just runs more stable with a set size. I recommend setting it to 32 GB.
If that doesn't do the trick or you've already done that, then we'll need to see the logs to see why it's crashing. If you get the pop up saying something like "Oops the game has crashed..." then it mentions a folder, which contains a few helpful files. To find it go to your game Library in Steam, right click on Cities Skylines, select Properties, go to the tab called Local Files and click the button Browse Local Files. Then upload those files somewhere and link to them here.
If you don't get the pop up, there is still the output log (called player.log on Mac and Linux). This guide explains where to find it, and recommends some places you can upload the files to as well.