[2020] Maximum Mods and Assets / Máximo de Mods y Assets Cities Skylnes

How many assets can I install on [xx]GB RAM?
It depends on the size of the assets. The game runs on the Unity engine, which loads all assets directly into the RAM on game load. so a 60MB train station uses 60MB RAM. A 10KB prop only uses 10KB, and so you can subscribe to a lot more before reaching the limit.

The average rule of thumb for the base game is:
4GB: 0-10 assets
8GB: 100-400 assets
12GB: 400-800 assets
16GB: 800-1200 assets
24GB: 1200-2000 assets
32GB: 2000-2800 assets
64GB: 2800-6000 assets

From the FAQ

How many DLCs you have also plays a part, since they also contain assets that take up RAM.

For mods it's really a question of what kind of mods you get, what system you have and what kind of performance you are fine with. Some mods can help the game run better, some will make it look better, some will make the game's AI smarter, some make the game more realistic. Mods do a lot of different things and so affect performance in many different ways.

If you're new to modding, I really recommend this guide. It covers a lot of the basics and introduces you to different kinds of mods.

https://steamcommunity.com/sharedfiles/filedetails/?id=1411897315

As for my setup, I have just around the 3000 assets and ~90 mods. Most of the time my game runs around the 20 FPS, but my cities also aren't that large.