almost 4 years ago - Avanya - Direct link
Let's start by removing broken mods. Unsubscribe from these:

- Tree Brush (don't need it when you have Extra Landscaping Tools)
- Big City (don't need it with 81 tiles)
- More Beautification - get Find It 2 instead

I see that the Mod Compatibility Checker has checked your mods multiple times, which makes me wonder if you have done multiple loads. You have to restart the game after loading a city when using mods. Otherwise they get loaded "on top" of the first load, which breaks a lot of things.

With these mods removed and a fresh start of the game, does it then load?
almost 4 years ago - Avanya - Direct link
Ah, so you're getting a simulation error. There's a few mods that can help fix that, so let's try those. Subscribe to these:

https://steamcommunity.com/sharedfiles/filedetails/?id=667342976
https://steamcommunity.com/sharedfiles/filedetails/?id=529129546
https://steamcommunity.com/sharedfiles/filedetails/?id=1620588636

Enable them all, restart the game and then go to Options, find the Loading Screen Mod on the left, find Safe Mode and enable all options for Safe Mode. Then load your save. Did that work?