What champion turned out to be completely different to what Riot envisioned them to be?

Ok I know the title is a bit difficult to understand so I''ll try to explain this with an example

If you go back and actually watch the champion spotlight for Vayne you'll realize something really funny. She was designed to be a midlane AD assassin. Her Q was considered to be her primary ability and W was suppose to be just nice little damage on the side. She was also considered, believe it or not, a 'strong early game champ'. She is basically the prototype for the type of champion that eventually became Akshan. For her to then essentially go into the role of hyperscaling tank shredding marksmen who is played in botlane and toplane without any substantial changes to her kit really highlights the fact that even 13 years ago Riot had no idea where they were going with some of their champions.

Anyways are there any other champions like this? Of course this doesn't include champions that were reworked on purpose to go into different roles.