Use your farming produce on the Tool Leprechaun to note it (herbs, fruit, vegetables, etc.) There's also a right-click option to do this now.
You can right-click an effigy to select the skill you want without going through the dialogue.
You can go to Father Aereck in Lumbridge church to buy a better gravestone and unlock an extra reduction of death costs (up to 5%). The best gravestone requires King of the Dwarves quest.
For every 25 quest points you can claim one-time dice rewards from May, at the May's quest caravan near the Varrock lodestone. Rewards include a lot of coins and clue scroll items.
Diseased farming patches no longer die - they stay diseased until you cure them. This means you can use an amulet of farming as a permanent teleport to a specific location by keeping a patch diseased.
Use scrimshaws on each other to combine their timers (up to 24 hours).
Open the "Sale History" tab in the Grand Exchange. You can right-click a past offer to repeat it.
Buying the Spirit cape from Dungeoneering shop permanently reduces the cost of familiar's special attack by 20%. The cape can be in your bank or POH storage, and this still works.
You can recharge the Drakan's medallion using Congealed blood, instead of Blood runes. It will be much cheaper, and you can stack up to 25k charges (!) this way.
Right-click the aura button or the empty aura slot (in worn equipment) to access your favourited auras.
Use an item on a bank booth or deposit box to deposit it (doesn't require PIN).
Right-click the lodestone network button (near the minimap) to quickly choose your previous destination. You can also keybind this function.
When you finish a yak track task, the green chatbox message can be clicked to claim the rewards for that task even in combat (you can't open the yak track interface in combat otherwise).
Press the mouse wheel to rotate the camera.
When your run is disabled, you can hold Ctrl + click somewhere to run there.
Right-click the first tab in your bank (infinity symbol) to select if you want your bank tabs positioned vertically or horizontally.
Springs and silverhawk feathers can be right-clicked to "add all".
You can drag any empty equipment slot to the action bar (when it is unlocked), and whatever you have equipped in that slot will show on your action bar.
Right-clicking the toolbelt button (below worn equipment screen) brings up the settings for all items you added to your toolbelt, such as seedicide, bonecrusher, charming imp, etc.
Left-clicking on the adrenaline bar uses your weapon's special attack. Left-clicking on the HP icon above the action bar cures you when you're poisoned and have antipoison with you. Left-clicking on the summoning bar toggles between displaying Summoning points and your familiar's special move points.
There's an in-game calendar which can be accessed by right-clicking the in-game clock.
If you add a D&D to favourites in the Minigames tab, you can check the cooldown of favourited activities by mousing over the star icon to the left of the in-game clock. Has to be enabled in settings under "Interfaces" and "Game Clock".
You can click a button in bottom-left of the emotes tab to toggle between displaying emote names in text or emote pictures.
In the emotes tab there's a sub-interface in which you can store transmog items.
You can combine partially eaten jellies if you speak to War at the PvM hub.
Mousing over your clan name tells you how many players are in your clan.
You can zoom in or out on the minimap.
Clicking on memory strands in the currency pouch teleports you to Memorial of Guthix and Hall of Memories.
Right-clicking the settings cog on the action bar is a quick way from EoC to Legacy combat mode.
Dive and Bladed Dive abilities can be used on minimap as well.
Using Bladed Dive on a frog in Big Game Hunter makes you dive to it and immediately start gathering poison.
You can sort quests in the Adventures interface, in "Quest" tab.
Right-click the arrival portal on the floor in War's retreat (PvM hub) to go to Death's office or Draynor crossroads.
Using the teleport option on your Captain's log while inside your player-owned port will teleport you outside.
You can get a Grim gem from Death to request reaper tasks remotely.
You can disable daily challenges in skills you have maxed by speaking to the challenge mistress.
Loot interface can be resized in "Edit Layout Mode" to eliminate scroll bar.
The so-called "extra action button" (which is used at Solak, Raksha, Kerapac, Zuk, and Zamorak) can be keybound.
Pressing Shift + Left/Right arrow keys moves the cursor when typing in chat.
One of the GE clerks in Prifddinas has a teleport option to Varrock GE, accessed via a chat option.
A cup of tea clears the effect of aggression potion.
When you have your weapons sheathed, you display your total level to other players. If unsheathed, combat level. You can sheathe/unsheathe by right-clicking the "minimise" button in top right of action bar (default keybind: * on numpad)
If you drag an item from your backpack over your worn equipment interface, the slot in which the item can be equipped will be highlighted.
In the Make-X interface you can left-click on the number of items to make to input digits, then press Enter (instead of playing with the +/- slider for exact amount).
If you right-click on a bank tab, you can choose a name for it, and a different symbol than the first item in the tab, for example a skill icon.
7 daily reset tokens can be right-click combined into a weekly reset token. 4 weekly reset tokens can be combined into a monthly reset token.
Dragon trinkets can be converted to Metallic dragon trinkets and vice versa (at a 5:1 rate).
You can put Arc teleport tablets inside the Arc journal, and Menaphos teleport tablets inside the Menaphos journal.
If you drag an item over the money pouch, you will alch it, provided you have the appropriate runes with you.
Every Thursday you can get some gossip from the barmaid in player-owned ports, which puts a really generous resource voyage in the 3rd voyage slot.
Before capping in the clan citadel, you can use the "avatar control stone" located near the avatar pool, to enable the citadel skill plot boost and cap 50% faster with the same XP. After you cap, you can then enable your usual 6% XP boost for the week.
Every week, once you've capped in your citadel, you can right-click your clan cloak to gain a small XP lamp worth of XP in any skill.
Some boss portals (in PvM hub and Max Guild) can be right-clicked to choose an arrival point outside or inside the boss lair.
It is possible to have one of each of the achievement diary items. You can for example have four different Tirannwn quivers with different ammo in them.
You can right-click the lectern in the base camp on Anachronia to set the delay between double surges and double escapes.
You can right-click the "workers" button in Anachronia base camp management to input the number of workers from keyboard instead of clicking the +/- buttons.
You can enable an effect that makes the edges of your screen turn red when you're close to dying. This setting is in Runemetrics settings in "Metrics" tab, as "Show health warning".
The worn equipment tab can be resized like all other tabs. If you make it large, it will show your character with worn slots around them. If you make it smaller, it will show the traditional skeleton layout with worn slots. If you make it even smaller, it will just show worn slots close together, similar to the backpack.
You can toggle between new and old minimap icons in Settings under "Legacy" header.
You can also disable the stupid boat travel cutscene in the settings, under "Interfaces" -> "Game interaction" (at the bottom).
You can combine all greegrees into one by using them on each other, to save bank space.
You can also combine all four soulstones from GWD into one item by using them on each other near the altar in the centre of GWD.
If you accidentally fill an ushabti you didn't mean to fill, you can right-click release the soul.
You can move monsters between rooms in your player-owned Slayer dungeon. This feature can be purchased from a Slayer master.
You can create many unfinished smithing objects, and then smith all of them.
Mousing over the Voice of Seren overlay symbols in Prifddinas shows the effects of each voice.
When someone places an achievement banner, if you add its owner to your ignore list, the banner will shut up.
You can right-click the skull symbol on your Slayer counter to switch between Slayer and Reaper tasks, and access both collection logs.
If you often use urns while skilling, consider making the Urn enhancer.
When making Vulnerability bombs for Herblore, you can store the ingredient runes in a rune pouch and wear it, to gain backpack space for more herbs.
The Fang of Mohegan is a necklace that offers one teleport a day to any Summoning obelisk in the game (minus Menaphos). As a result, it has many completely unique teleports, including a teleport to inside of the Underground Pass. You can check Diango's storage to see if you own one.
You can right-click an outfit piece at Diango to retrieve the whole outfit.
You can use most containers (gem bag, herb bag, seed bag, ore box, plank box, soil box, etc.) on bankers, bank counters, or deposits to dump the contents inside. You can also empty them with the bank open.
You can right-click and name each of your four customisation outfit presets in the Wardrobe interface (text input prompt, not just preset names).
The buttons in your Summoning familiar's details screen - you can drag most of them to the action bar (when it is unlocked).
In the Camera settings you can choose one of the two "freedom" modes (for either modern or classic camera), which allows for longer zoom-in and zoom-out on your character.
After the City of Senntisten quest you can overcharge your Pontifex ring by giving 5k of each elder god anima to Wahisietel in Senntisten cathedral. This will make the ring work in Elder GWD at all times, passively, from bank.
You can visit Explorer Jack in Lumbridge (near the general store) to collect a large amount of money as a reward for completing Achievement Diaries (task sets).
In Gameplay settings under "Skills", in the Construction section, you can set whether you teleport to house puts you inside or outside of the POH portal.
You can use spirit gems of the same type on each other to combine their charges up to a thousand charges.
The charming imp can also destroy spirit gem drops for you.
You can unlock an upgrade to Bonecrusher that makes it automatically pick up bones that aren't crushed. This can be toggled in Bonecrusher settings (at the bottom). You can buy this unlock in the rewards shop on Waiko.
You can unlock upgrades to Herbicide and Seedicide that make them automatically pick up herbs and seeds that aren't destroyed. This can be toggled in Herbicide and Seedicide settings (at the bottom). You can buy these unlocks in the farmers' market on the Player-owned Farm.
Elnock in Puro-Puro will store your Magic butterfly net. Bank space saved.
You can right-click a Replenishment potion to drink just the super restore, while the adrenaline effect is on cooldown.
A plank box can be used when making flatpacks (this includes on portable workbench) - the planks will be taken from it automatically.
NPCs who decant potions will also decant them noted.
Ground mud runes are now tradeable.
The Chronicle Attraction prayer will also automatically siphon your manifested knowledge and divine carpet dust (not mentioned in the tooltip).
When you right-click the main action bar number, you can see the list of your action bars, and what you have named them.
Crystal knife activates its effect when making shafts for dinarrows, and doesn't degrade if used this way.
If you're a premier member, you can open the oddments store and go to the "Benefits" tab, and collect a "Monthly Drop".
You can right-click a preset number button to quickly save it.
The slim headers option in settings (Interface -> Appearance) removes words like "backpack" and "prayers" out of your UI.
You can store crystal seeds and attuned crystal seeds at Lady Ithell in Prifddinas (right-click "Exchange"). Bank space saved.
There is an ability in Constitution that will eat the first piece of food from your inventory.
Invention charges for machines in the Invention Guild may be freely stored and withdrawn from the generator.
Skilling tools and off-hands (tinderbox, hammer, fishing rod, artificer's measure, orthen core, etc.) can be used to bladed dive with.
Area loot is larger when playing on mobile (17x17 instead of 7x7).
After you do the Animal Magnetism quest and hit level 50 Ranged, all ammo is picked up passively without having to wear the Ava's device.
You can use a cleaning cloth to wipe the colour off an Essence of Finality amulet, Grasping rune pouch or Pernix's quiver.
You should check the Het's Oasis water filtration system once a month to collect free items. After you collect once, click again for a second screen of loot.
You can teleport directly to Wilderness flash events by right-clicking the event NPCs in Edgeville (starting 5 minutes before the event).
If you use the Crystal Mask spell from your action bar, it will not interrupt skilling actions (pickpocketing Crux Eqal Knights, gathering at Croesus). This also applies to other spells, and items such as the ancient elven ritual shard and Excalibur. Use them from the action bar instead of spellbook/backpack.
You can put a skillcape on a rack in your base camp on Anachronia (in the player lodge) to gets its perk passively. You can put a slayer helmet on a stand in your slayer lodge too.
Right-click the aura refresh scrolls to store them inside your aura interface. Bank space saved.
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