Hello all!
I was playing AC Origins for the first time when it didn't launch. I know many people have this issue, and I have found a fix. (note that this fix is for the official game version. I do not know if it works for cracks)
1st Solution
Your game is most likely on a Microsoft Storage Device. For some reason, it is the cause of this issue. Simply move the game files to an other drive. For me, it was my main "C:" SSD drive.
Now, I know many might not have space on that other drive. If so, the next solution will help you with that.
2nd Solution
1- Locate the "sounddata" folder inside the game installation folder. ("\Ubisoft\Ubisoft Game Launcher\games\Assassin's Creed Origins\sounddata" probably)
2- Move "sounddata" folder to anywhere on your C:\ drive. (I moved it to "C:\Users\\Documents\AC origins\sounddata")
3- Remove the "sounddata" folder from the Assassin's Creed Origins installations folder, or rename it to something else. However we won't need this folder any longer so removing it won't hurt.
4- Open CMD in administration mode and navigate to the folder where you put the "sounddata" folder on the C:\ drive with:
cd "C:\Users\\Documents\AC origins"
5- Make a hard link syslink from the filesynced folder on C:\ to the Assassin's Creed Origins installation folder on your other drive with:
mklink /J "E:\\Ubisoft\Ubisoft Game Launcher\games\Assassin's Creed Origins\sounddata" "C:\Users\\Documents\AC origins\sounddata"
6- Start the game via Uplay as usual.
More info about the mklink command
I hope this guide helped you resolve your issue. Please tell me if you notice any errors in my post.