[2020] Is there a plan to include non-aligned champions in the game ?

Hi! I'm Dovagedys, the Product Lead for "Sets" on Legends of Runeterra.

I think this is an awesome question and want to share some of our thinking regarding future champions.

Over time we hope to eventually include every champion in Legends of Runeterra. There are many factors that determine when we include a champion. The most important factors are gameplay and thematic cohesion. We want the champions to feel like they belong together, play well together, and are fun together. As we begin releasing expansions and add more champions, we want to ensure they’re exciting and fun for players, thematically fit with their expansion as a whole, represent new mechanics, and work well in an ecosystem with all the previously released champions.

As you mentioned, champions are often related to specific regions and we take that into account when considering which champions to include in future expansions. However, I believe there are creative ways to include champions that aren't currently associated with a specific region. There are so many champions from League of Legends that aren't associated with a Region. I don't think that factor would lead to a champion being excluded from Legends of Runeterra forever.