Because of this modifier on Reap's skill gem, spell damage modifiers will work the same way as damage over time modifiers, so poisons you apply with reap will be modified by pain attunement and other spell damage increases/more multipliers.
While afaik spell damage doesn't affect poisons you apply with BV. So unfortunately there's not much synergy if you go reap+bv poison and stack spell damage, your reap will have good damage with poison but the spell damage wont buff BV poison.
Edit: nevermind, this doesn't work anymore. My old ass building knowledge is showing lmao.
The mod that Reap and Essence Drain now only works for the skill's own DoT, it used to work for ignite/poisons but doesn't anymore. Build ruined.