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Whenever I play The Division 2 my mic will stop working across my entire PC, Discord will stop picking up my mic, even windows will stop recognizing the mic. I've changed to a different mic and had the exact same issue happen. Both mics drivers are up to date, doesn't matter if I unplug the mic and plug it back in. Mic will start working again when I close Division 2. I've had it where I played for a few hours and not had it happen, and I've had it happen 3 minutes into playing, mostly happens within the first 10 minutes of the game being open.
I've played Division 2 before on this exact same PC, had no issues played for 30hrs. I even had the same mic back then when I first played!