This seems to be the same problem as reported here:
https://forums.ubisoft.com/showthread.php/2198153-***-BUG-***-The-Wall-Street-Main-Mission
The caches/supplies can not be opened.
On the first try through the mission I was killed while trying to open one cache during combat.
On the second playthrough one cache was grayed out, but seemed to be required.
On the following tries sometimes a single cache was accesible.
Also encountered this sometimes on supply drop activities, caches at end of other activities (e.g. territory control) and even special amo caches (explosive, incendiary, ...). While these are annoying, the bug listed above is game breaking, as it prevents progress in the mission.