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External link →I woke up to the same issue and I haven't had a single issue with Vanguard or Valorant since beta release on 7th April. Uninstalling both Vanguard and Valorant doesn't make a difference, Vanguard won't initiate.
Edit: I fixed this by disabling everything but vgc in services (with exclude Microsoft services ticked) and rebooted system. It's odd since I have never had an issue with Vanguard until this morning despite playing several hours a day since start of beta.
I don't know if it'll help your specific issue but we have a Vanguard update coming soon (possibly today, otherwise likely Monday) with bug fixes.