Hello,
I play Anno 1800 with all major DLC an no mods on sandbox mode unrelated to the campain or any scenario.
Since the last DLC release, the game crashes sometines because it could not allocate more memory. Progressing further in the game made crashes more frequent (very annoying when the minimal automatic save is only 5 minutes).
However the last crash seemed to break my savegame, I let you see the following screenshot :
After 3 restart I now get systematically a memory crash after each load.