almost 2 years ago - TigerCr4ne - Direct link

What we announced in the June dev update, all tuning orbs in your inventory (including mutator orbs) will be transformed into item caches that roll on Expedition specific bosses. Since mutator orbs are agnostic of expedition they will roll on multiple bosses. They still won’t be as valuable as running an expedition outright, but more details will come in our patch notes.