almost 4 years ago - AndrewT - Direct link
Please do a full **clean** re-install:

- move any valued save games elsewhere
- "uninstall" in Steam-CK3
- manually delete both the Steam/SteamApps/common/CK3 AND Documents/Paradox/CK3 folders
- re-install game in Steam, run a Steam Verify when done.
- add CK3.exe to the exceptions list of your antivirus app; ESPECIALLY if you have Windows Defender, add it to the Ransomware "Apps Allowed Through" list.
- start the game with no mods active and test

In particular make sure there are no files or folders left under either the Steam CK3 or Documents CK3 locations, before installing again.  
almost 4 years ago - AndrewT - Direct link
Interesting, the second case I've seen with Vermintide in this thread today ... anyway we're still seeing the errors in the graphics card area there. Please try this:

- uninstall the AMD video driver with this tool:
https://support.amd.com/en-us/kb-articles/Pages/AMD-Clean-Uninstall-Utility.aspx - reboot
- install the one from May 2020 from here:
http://support.amd.com/en-us/download - reboot again

Also, if you run the Windows Updater app you should see a whole new Windows 10 version is available to install. Can you try that please?