[2022] CK3 Crashing/Refusing to Launch

Does running ck3.exe direct;ly do anything?

If not Please go here:

Latest supported Visual C++ Redistributable downloads

This article lists the download links for the latest versions of Visual C++ Redistributable packages. support.microsoft.com And run the x86 and x64 installers there.

Then run this Windows repair tool:

Use the System File Checker tool to repair missing or corrupted system files

Describes how to use the System File Checker tool to troubleshoot missing or corrupted system files in Windows 8.1, Windows 8, Windows 7 or Windows Vista. support.microsoft.com
Does that help at all?