This is a well-known problem for NVIDIA users. You can see the issue in the previous forum and it was never resolved. Below is the link.
https://forums.ubisoft.com/showthread.php/2304972-Latest-NVIDIA-drivers-result-in-low-fps-after-certain-time-Forums/page7
If you play ANNO 1800 for 3-4 hours, your PC starts stuttering, the framerate drops and the game becomes unplayable at some point because it is too laggy no matter how powerful your rig is. It destabilizes the PC, your system keeps stuttering even after exiting the game. You have to reboot the system to save your system and yourself from this horror.
Only the workaround of the issue is to install the outdated driver v457.51 like you have no video games to play other than ANNO 1800. Someone says it has something to do with the animated cursors. There is a mod to disable it and some say it fixes the problem. I have not tried it myself so I don't know if it is true. Here is the link. https://www.nexusmods.com/anno1800/mods/118/?tab=description
My question is "Are you actually going to fix the problem or are you going to keep ignoring it?". You will probably say it is NVIDIA's problem as you did before. I say it is still your [censored] responsibility to address the issue to NVIDIA and get the problem fixed even if that is true.