The big distinction here is that we don't have a fully offline mode yet. So, nothing has changed on this front yet. When we do have a proper fully offline mode, we will likely be very hands off with it. Our major concern with game integrity comes with online mode.
Edit: I just read that statement and some things have changed. The online and offline modes are going to be part of a single client now. We will have to reevaluate how we are going to handle people making mods.