Hey you seem like you know what you’re talking about - are keybinds to hardware devices - say binding attack move click to the “A” key, then binding the “A” key to a side mouse button - allowed in league? Sorry to waste your time with a dumb question.
Yeah, remapping like this shouldn't pose any issue that I know of. There are artificial input checks we have in VALORANT that can be blocked, but these aren't applicable to League of Legends, and these remappings aren't "artificial input", just input in a different form.