Most likely you are indeed running out of available memory. First expand your Windows paging file maximum size to 32gb
Some crashes in the AMD driver shown in there (not apparently to do with the game as such), so let's do a clean reinstall
- uninstall with this https://support.amd.com/en-us/kb-articles/Pages/AMD-Clean-Uninstall-Utility.aspx
- reboot
- install the latest http://support.amd.com/en-us/download
- reboot again
THEN Right click on eu4.exe , properties, compatibility. Tick "disable fullScreen optimisations" untick every other box in that dialog, Apply and exit.
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